产品货号:
Z20431
中文名称:
MEK4/MAP2K4抗体
英文名称:
Anti-MEK4/MAP2K4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MEK4/MAP2K4 Antibody |
指标别名 | JNK activating kinase 1;JNKK;JNKK1;MAP kinase kinase 4;MAP2K4;MAPK/ERK kinase 4;MAPKK 4;MAPKK4;MEK 4;MEK4;MKK4;PRKMK4;SAPK/ERK kinase 1;SEK1;SERK1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ELISA |
基因名称 | MAP2K4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MEK4(360-378aa ELLKHPFILMYEERAVEVA),different from the related mouse and rat sequences by one amino acid. |
实际分子量 | 44KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Dual specificity mitogen-activated protein kinase kinase 4(MAP2K4),also called SEK1 or JNKK1,is an enzyme that in humans is encoded by the MAP2K4 gene.It is mapped to 17p12.This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family.This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli.It has been shown to activate MAPK8/JNK1,MAPK9/JNK2,and MAPK14/p38,but not MAPK1/ERK2 or MAPK3/ERK1.This kinase is phosphorylated,and thus activated by MAP3K1/MEKK.MAP2K4 was a specific activator of JNK1,JNK2,and p38,and it has been shown to interact with FLNC,MAPK8,MAPK8IP3 and AKT1. |
Uniprot ID | P45985 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | mitogen-activated protein kinase kinase 4 |
蛋白名全称 | Dual specificity mitogen-activated protein kinase kinase 4 |
推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 |
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